BLOC1S1 | |||||||||
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Identifiers | |||||||||
Aliases | BLOC1S1, BLOS1, GCN5L1, MICoA, RT14, BORCS1, biogenesis of lysosomal organelles complex 1 subunit 1 | ||||||||
External IDs | |||||||||
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Orthologs | |||||||||
Species | Human | Mouse | |||||||
Entrez | |||||||||
Ensembl | |||||||||
UniProt | |||||||||
RefSeq (mRNA) | |||||||||
RefSeq (protein) | |||||||||
Location (UCSC) | Chr 12: 55.72 – 55.72 Mb | Chr 10: 128.92 – 128.92 Mb | |||||||
PubMed search | [3] | [4] | |||||||
Wikidata | |||||||||
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Rave report 11 keygen software download. Biogenesis of lysosome-related organelles complex 1 subunit 1 is a protein that in humans is encoded by the BLOC1S1gene.[5][6][7] Fl studio 12 4 for mac download.
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BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. 2do 2 0 download free. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004).[supplied by OMIM][7]
Interactions[edit]
BLOC1S1 has been shown to interact with BLOC1S2,[6]SNAPAP[6] and PLDN.[6]
References[edit]
3-1-1 Rule
- ^ abcGRCh38: Ensembl release 89: ENSG00000135441 - Ensembl, May 2017
- ^ abcGRCm38: Ensembl release 89: ENSMUSG00000090247 - Ensembl, May 2017
- ^'Human PubMed Reference:'. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^'Mouse PubMed Reference:'. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^Inoue M, Isomura M, Ikegawa S, Fujiwara T, Shin S, Moriya H, Nakamura Y (Jul 1996). 'Isolation and characterization of a human cDNA clone (GCN5L1) homologous to GCN5, a yeast transcription activator'. Cytogenet Cell Genet. 73 (1–2): 134–6. doi:10.1159/000134324. PMID8646881.
- ^ abcdStarcevic M, Dell'Angelica EC (Jun 2004). 'Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)'. J Biol Chem. 279 (27): 28393–401. doi:10.1074/jbc.M402513200. PMID15102850.
- ^ ab'Entrez Gene: BLOC1S1 biogenesis of lysosome-related organelles complex-1, subunit 1'.
External links[edit]
- Human BLOC1S1 genome location and BLOC1S1 gene details page in the UCSC Genome Browser.
Further reading[edit]
Blocs 3 1 1 Rom Coms
- Watanabe TK, Fujiwara T, Shinomiya H, et al. (1997). 'Molecular cloning of a novel human cDNA, RT14, containing a putative ORF highly conserved between human, fruit fly, and nematode'. DNA Res. 2 (5): 235–7. doi:10.1093/dnares/2.5.235. PMID8770567.
- Ogryzko VV, Kotani T, Zhang X, et al. (1998). 'Histone-like TAFs within the PCAF histone acetylase complex'. Cell. 94 (1): 35–44. doi:10.1016/S0092-8674(00)81219-2. PMID9674425. S2CID18942972.
- McMahon SB, Wood MA, Cole MD (2000). 'The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc'. Mol. Cell. Biol. 20 (2): 556–62. doi:10.1128/MCB.20.2.556-562.2000. PMC85131. PMID10611234.
- Kurooka H, Honjo T (2000). 'Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5'. J. Biol. Chem. 275 (22): 17211–20. doi:10.1074/jbc.M000909200. PMID10747963.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). 'Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences'. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC139241. PMID12477932.
- Mishra SK, Mazumdar A, Vadlamudi RK, et al. (2003). 'MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functions'. J. Biol. Chem. 278 (21): 19209–19. doi:10.1074/jbc.M301968200. PMID12639951.
- Lehner B, Semple JI, Brown SE, et al. (2004). 'Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region'. Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID14667819.
Blocs 3 1 1 Rom Coms
Interactions[edit]
BLOC1S1 has been shown to interact with BLOC1S2,[6]SNAPAP[6] and PLDN.[6]
References[edit]
3-1-1 Rule
- ^ abcGRCh38: Ensembl release 89: ENSG00000135441 - Ensembl, May 2017
- ^ abcGRCm38: Ensembl release 89: ENSMUSG00000090247 - Ensembl, May 2017
- ^'Human PubMed Reference:'. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^'Mouse PubMed Reference:'. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^Inoue M, Isomura M, Ikegawa S, Fujiwara T, Shin S, Moriya H, Nakamura Y (Jul 1996). 'Isolation and characterization of a human cDNA clone (GCN5L1) homologous to GCN5, a yeast transcription activator'. Cytogenet Cell Genet. 73 (1–2): 134–6. doi:10.1159/000134324. PMID8646881.
- ^ abcdStarcevic M, Dell'Angelica EC (Jun 2004). 'Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)'. J Biol Chem. 279 (27): 28393–401. doi:10.1074/jbc.M402513200. PMID15102850.
- ^ ab'Entrez Gene: BLOC1S1 biogenesis of lysosome-related organelles complex-1, subunit 1'.
External links[edit]
- Human BLOC1S1 genome location and BLOC1S1 gene details page in the UCSC Genome Browser.
Further reading[edit]
Blocs 3 1 1 Rom Coms
- Watanabe TK, Fujiwara T, Shinomiya H, et al. (1997). 'Molecular cloning of a novel human cDNA, RT14, containing a putative ORF highly conserved between human, fruit fly, and nematode'. DNA Res. 2 (5): 235–7. doi:10.1093/dnares/2.5.235. PMID8770567.
- Ogryzko VV, Kotani T, Zhang X, et al. (1998). 'Histone-like TAFs within the PCAF histone acetylase complex'. Cell. 94 (1): 35–44. doi:10.1016/S0092-8674(00)81219-2. PMID9674425. S2CID18942972.
- McMahon SB, Wood MA, Cole MD (2000). 'The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc'. Mol. Cell. Biol. 20 (2): 556–62. doi:10.1128/MCB.20.2.556-562.2000. PMC85131. PMID10611234.
- Kurooka H, Honjo T (2000). 'Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5'. J. Biol. Chem. 275 (22): 17211–20. doi:10.1074/jbc.M000909200. PMID10747963.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). 'Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences'. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC139241. PMID12477932.
- Mishra SK, Mazumdar A, Vadlamudi RK, et al. (2003). 'MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functions'. J. Biol. Chem. 278 (21): 19209–19. doi:10.1074/jbc.M301968200. PMID12639951.
- Lehner B, Semple JI, Brown SE, et al. (2004). 'Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region'. Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID14667819.